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Identification of the Receptor for Activated Protein Kinase C1 (RACK1) Interacting Protein (s) in Black Tiger Shrimp (Peneaus monodon)


Identification of the Receptor for Activated Protein Kinase C1 (RACK1) Interacting Protein (s) in Black Tiger Shrimp (Peneaus monodon)


Identification of the Receptor for Activated Protein Kinase C1 (RACK1) Interacting Protein (s) in Black Tiger Shrimp (Peneaus monodon) Amonrat Pongdara and Monthira Thonganan Abstract :  A gene encoding a receptor for activated protein kinase C1 homolog has been isolated from the shrimp, Penaeus monodon (Pm-RACK1). The full length Pm-RACK1 cDNA has 954 bp, and an open reading frame encoding a protein of 318 amino acid residues. The protein contains seven WD40 repeats and shares approximately 78% identity with vertebrate RACK1. In adult shrimp, Pm-RACK1 transcripts were detected in all tissues. During WSSV infection, Pm-RACK1 was upregulated in hepatopancreas, stomach and hemocytes. We identified Pm-RACK1 as a specific cellular target protein for VP9, a nonstructural protein of WSSV. The interaction of these two proteins may be involved in mediating intracellular VP9 functions. Keyword : RACK1 Source : https://tarr.arda.or.th/preview/item/51998?keyword=กุ้งกุลาดำ
Administrator 2010-09-30

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